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Thioflavin T

Name: Thioflavin T
Brand: ARNISH LABORATES PRIVATE LIMITED.
Price: 1 INR
Availability: InStock

Price 1 INR/ Kilograms

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MOQ : 25 Kilograms

Thioflavin T Specification

Purity
>98% (HPLC)

HS Code
32049000

Poisonous
Yes (handle with care)

Properties
Fluorescent dye, used as a histology stain for amyloid fibrils detection

Usage
Suitable for laboratory research and diagnostics

Ph Level
Neutral in solution

Melting Point
155-159C

Physical Form
Powder

Grade
Analytical Reagent (AR), Laboratory Grade

Structural Formula
C17H19ClN2S

EINECS No
219-232-0

Taste
Not determined

Appearance
Yellow to greenish-yellow crystalline powder

Molecular Weight
318.87 g/mol

Product Type
Organic Compound

Smell
Odorless

Shape
Crystalline

Application
Biological staining, amyloid detection, fluorescent probe

Molecular Formula
C17H19ClN2S

Density
Gram per cubic centimeter(g/cm3)

Ingredients
Thioflavin T

Solubility
Soluble in water, ethanol, methanol

Refractive Rate
Not determined

CAS No
2390-54-7

Shelf Life
24 months

Storage
Store at 2-8C, dry and protected from light

Fluorescence Emission
482 nm (upon binding amyloid)

Stability
Stable under recommended storage conditions

Transport Information
Non-dangerous for transport as per IATA/IMDG

RTECS Number
XT9456900

Hazard Statement
Irritant, potential health hazard, use protective equipment

Disposal
Dispose of according to local regulations

Synonyms
Basic yellow 1, ThT, CI 49005

Absorption Maximum (max)
412 nm (in water)

Boiling Point
Not applicable (decomposes)

Packing Details
Sealed in light-resistant container

UN Number
Not regulated

Thioflavin T Trade Information

Minimum Order Quantity
25 Kilograms

Supply Ability
100 Kilograms Per Week

Delivery Time
1 Week

About Thioflavin T

THIOFLAVIN T

We are a reliable manufacturer, exporter and supplier of supreme quality THIOFLAVIN T. The offered chemical is extensively used to determine trace amounts of Cu in wine. It is formulated using the best quality chemicals under favorable conditions by our highly skilled professionals. Apart from this, the provided THIOFLAVIN T is made available in bulk at marginal prices for our clients.

Features:

Longer shelf life
Accurate pH value
Highly reactive
Better chemical stability

Key Properties and Analytical Grade Quality

Thioflavin T features a purity greater than 98% (HPLC) and serves as a reliable histology stain for amyloid fibrils detection in laboratory research. Its crystalline powder form is odorless and maintains stability under recommended storage. Being non-hazardous for transport as per IATA/IMDG, it is conveniently shipped in tightly sealed, light-resistant containers to maintain integrity and shelf life.

Application in Biological and Diagnostic Research

Widely used as a fluorescent probe, Thioflavin T is integral in visualizing amyloid deposits, making it essential in research on neurodegenerative disorders. It displays bright fluorescence upon binding to amyloid structures, offering scientists a clear advantage in amyloid quantification and localization. Suitable for both research and diagnostic environments, its application extends to various analytical protocols.

FAQs of Thioflavin T:

Q: How is Thioflavin T used in laboratory research?

A: Thioflavin T is typically utilized as a fluorescent dye to stain and detect amyloid fibrils in biological samples. When it binds to amyloid structures, it emits fluorescence at 482 nm, making it valuable for visualizing and quantifying amyloid deposits in diagnostic and research protocols.

Q: What safety precautions should be followed when handling Thioflavin T?

A: Due to its potential irritant and poisonous nature, personal protective equipment such as gloves, lab coats, and eye protection should be worn. Work in a well-ventilated area and avoid direct inhalation or contact. Dispose of any waste according to local regulations.

Q: When should Thioflavin T solutions be prepared for optimal results?

A: For best fluorescence properties and consistent results, prepare Thioflavin T solutions fresh before each experiment. Always use analytical grade solvents and protect the dye from exposure to light during preparation and use.

Q: Where should Thioflavin T be stored to maximize shelf life?

A: Store Thioflavin T at a temperature between 28C in a dry environment and protect it from light by keeping it in its original, tightly sealed light-resistant container. Under these conditions, the product retains its quality for up to 24 months.

Q: What is the process for staining amyloid fibrils using Thioflavin T?

A: Begin by preparing a suitable concentration of Thioflavin T solution in water or alcohol. Apply the solution to the biological specimen, incubate according to optimized protocols, then wash off excess dye. Examine the sample under a fluorescence microscope to observe and quantify amyloid structures, utilizing the characteristic strong fluorescence of ThT upon binding.

Q: What are the benefits of using Thioflavin T in amyloid detection?

A: Thioflavin T delivers high sensitivity and specificity in detecting amyloid fibrils, enabling clear visualization thanks to its bright fluorescence. Its use accelerates the identification and quantification of amyloids, supporting advanced research in neurodegenerative diseases and related diagnostics.

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